Category Archives: Research

Squaramides as potential anticancer agents for gastric carcinoma

Posted on March 9, 2016 by mmaamarq

These are the first results on a recently published study investigating the anticancer activity of squaramides carried out in collaboration with our collegue and friend Dr. Gemma Triola (IQAC-CISC). This article is part of a themed collection: Special issue devoted to “New … Continue reading →

Posted in Biological activity, Cancer, Collaboration, Publication, Research, Squaramide, Synthesis | Tagged 2016, Biological activity, Collaboration, Eugenia Marqués-López, Gemma Triola, Human gastric carcinoma cells HGC-27, Juan V. Alegre-Requena, Med. Chem. Commun., Publication, Raquel P. Herrera, Squaramide | Leave a comment

Learn about more properties of squaramides!

Posted on January 27, 2016 by mmaamarq

This is a nice fruit of the intensive and intriguing collaboration between our research group and Prof. Gimeno’s group (ISQCH). Congratulation guys! “Synthesis of Luminescent Squaramide Monoesters: Cytotoxicity and Cell Imaging Studies in HeLa Cells” Fernandez-Moreira, V.; Alegre-Requena, J. V.; Herrera, R. … Continue reading →

Posted in Biological activity, Collaboration, Fluorescence, Publication, Research, Squaramide, Synthesis | Tagged 2016, Cell Imaging, Cytotoxicity, Fluorescence, Juan V. Alegre-Requena, Prof. Gimeno, Publication, Raquel P. Herrera, RSC Advances, Squaramide, Synthesis | Leave a comment

HOCA-guys spent a few days in Barcelona, in the “XII Symposium of young researchers” (XII SIJ, RSEQ-Sigma Aldrich)

Posted on November 10, 2015 by mmaamarq

The last edition of the “Simposio de Investigadores Jóvenes, RSEQ-Sigma Aldrich” (XII SIJ) has been held in Barcelona from 3-6 November, and our group has been well represented by Fernando, Juanvi and Isaac. They presented their research work and enjoyed … Continue reading →

Posted in Conference, Dihydropyridines, Meeting, Organocatalysis, Research, Spirooxindole, Squaramide, Urea | Tagged 2015, Asymmetric organocatalysis, Fernando Auria-Luna, Isaac G. Sonsona, Juan V. Alegre-Requena, Symposium, XII SIJ | Leave a comment

HOCA publishes a new method of addition of indoles to aliphatic β,γ-unsaturated α-ketoesters catalyzed by a chiral thiourea

Posted on June 18, 2015 by zco1999

“Thiourea-Catalyzed Addition of Indoles to Aliphatic β,γ-Unsaturated α-Ketoesters” by Verónica Juste-Navarro, Eugenia Marqués-López and Raquel P. Herrera has been published in Asian Journal of Organic Chemistry. DOI: 10.1002/ajoc.201500154 Abstract: The first thiourea-catalyzed addition reaction of indoles to aliphatic β,γ-unsaturated α-ketoesters has been developed. … Continue reading →

Posted in Organocatalysis, Publication, Research, Scientific dissemination, Thiourea | Tagged 2015, Aliphatic β γ-unsaturated α-ketoester, Asian J. Org. Chem., Asymmetric organocatalysis, Eugenia Marqués-López, Indole, Publication, Raquel P. Herrera, Synthesis, Thiourea | Leave a comment

“One-pot synthesis of unsymmetrical squaramides” just published in RCS Advances

Posted on April 8, 2015 by mmaamarq

Congratulations Juanvi for the recent publication of the “One-pot synthesis of unsymmetrical squaramides” in RCS Advances, 2015, 5, 33450-33462! DOI: 10.1039/C5RA05383H Abstract: The results concerning the first one-pot synthesis of unsymmetrical squaramides are reported. This straightforward procedure allows appealing and commonly used squaramide … Continue reading →