Tag Archives: Thiourea

A new article just come out!

Catalysis-free synthesis of thiazolidine–thiourea ligands for metal coordination (Au and Ag) and preliminary cytotoxic studies, Salvador-Gil, D.; Herrera, R. P.; Gimeno, M. C.  Dalton Trans. 2023. DOI: https://doi.org/10.1039/D3DT00079F. Abstract. The reaction of propargylamines with isothiocyanates results in the selective formation of … Continue reading

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Congratulations Guille for the first of many scientific articles!

Synthesis of New Thiourea-Metal Complexes with Promising Anticancer Properties, Canudo-Barreras, G.; Ortego, L.; Izaga, A.; Marzo, I.; Herrera, R. P.; Gimeno, M. C. Molecules 2021, 26(22), 6891. https://doi.org/10.3390/molecules26226891. Abstract. In this work, two thiourea ligands bearing a phosphine group in … Continue reading

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Overview on asymmetric fluorination reactions by means of ORGANOCATALYSIS

Asymmetric Fluorination Reactions Promoted by Chiral Hydrogen‐Bonding‐Based Organocatalysts, Auria-Luna, F.; Mohammadi, S.; Divar, M.; Gimeno, M. C.; Herrera, R. P. Adv. Synth. Catal. 2020, https://doi.org/10.1002/adsc.202000848 VIP Abstract. Fluorinated compounds can exhibit interesting biological properties. The importance of these species has made … Continue reading

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Metals… more and more present in the HOCA group, SOS!

Last week (14-15 November 2019), Raquel attended to the 1st International Workshop on Metals in Medicine hold at Chimie ParisTech, PSL University. She presented the poster entitle Synthesis of group 11 metal complexes with thiourea or squaramide ligands: study of … Continue reading

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A little tribute to (THIO)UREAS. Improving their organocatalytic activity…

Hydrogen bonding and Internal or External Lewis or Brønsted Acid Assisted (Thio)urea Catalysts, Gimeno, M. C.; Herrera, R. P. Eur. J. Org. Chem. 10.1002/ejoc.201901344 Abstract. The obtainment of more active organocatalysts has promoted the search for new modes of activation … Continue reading

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A synergistic couple of catalysts

A new article has just been accepted. Congratulations! Gold(I) mediated thiourea organocatalyst activation: A synergic effect for asymmetric catalysis. Anabel Izaga, Raquel P. Herrera, M. Concepción Gimeno, ChemCatChem, 2017, 10.1002/cctc.201601527. Abstract. Several group 11 metal complexes with chiral thiourea organocatalysts have … Continue reading

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Cheating on Organocatalysis…

Raquel attended the XXXIV GEQO Congress in Girona last week (7–9 September). Her scientific contribution was entitled “Gold(I) mediated thiourea organocatalyst activation: A synergic effect for asymmetric catalysis”.

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Wanna know what happens if you consider MOFs and HBC together? Take a look to this highlight, just published in CrystEngComm

The highlight entitled “Metal-organic frameworks (MOFs) bring new life to hydrogen-bonding organocatalysts in confined spaces” has just been published at CrystEngComm. In this work, together with Prof. David Díaz (Universität Regensburg), we have compiled and studied the literature which involves the intriguing idea of … Continue reading

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HOCA to publish a New Synthesis of Chiral 2-Oxospiro-[indole-3,4′- (1′,4′-dihydropyridines)]

We are interested in the enantioselective synthesis of highly functionalized molecules with biological activity. In this frame, we have just published “a preliminary study” in the development of a “New Organocatalytic Asymmetric Synthesis of Highly Substituted Chiral 2-Oxo Spiro-[indole-3,4′- (1′,4′-dihydropyridine)] … Continue reading

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HOCA publishes a new method of addition of indoles to aliphatic β,γ-unsaturated α-ketoesters catalyzed by a chiral thiourea

“Thiourea-Catalyzed Addition of Indoles to Aliphatic β,γ-Unsaturated α-Ketoesters” by Verónica Juste-Navarro, Eugenia Marqués-López and Raquel P. Herrera has been published in Asian Journal of Organic Chemistry. DOI: 10.1002/ajoc.201500154 Abstract: The first thiourea-catalyzed addition reaction of indoles to aliphatic β,γ-unsaturated α-ketoesters has been developed. … Continue reading

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