Category Archives: Organocatalysis

HOCA (aza-Henry reaction) in The 24th International Electronic Conference on Synthetic Organic Chemistry (Nov 2020)

Asymmetric aza-Henry reaction of hydrazones I. G. Sonsona, J. V. Alegre-Requena,* E. Marqués-López, M. C. Gimeno, R. P. Herrera* 10.3390/ecsoc-24-08411 (registering DOI) Abstract: In this work, the enantioselective organocatalyzed addition of nitroalkanes to N-benzoyl hydrazones has been developed for the … Continue reading

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HOCA initiation in DNA binding studies of compounds obtained through green methods

Ultrasound-assisted multicomponent synthesis of 4H-pyrans in water and DNA binding studies, Auria-Luna, F.; Fernández-Moreira, V.; Marqués-López, E.; Gimeno, M. C.; Herrera, R. P. Sci. Rep. 2020 , 10, 11594. https://doi.org/10.1038/s41598-020-68076-1 Abstract. A simple approach to synthesize new highly substituted 4H-pyran … Continue reading

Posted in DNA, Heterocycle, Multicomponent reaction, Organocatalysis, Publication, Pyrans, Research, Synthesis | Tagged , , , , , , , , , , , , , , , | Leave a comment

Just accepted, congratulations!

Asymmetric organocatalyzed aza‐Henry reaction of hydrazones: experimental and computational studies, Sonsona, I. G.; Alegre-Requena, J. V.; Marqués-López, E.; Gimeno, M. C.; Herrera, R. P. Chem. Eur. J. 2020, DOI: 10.1002/chem.202000232   Abstract. The first asymmetric catalyzed aza‐Henry reaction of hydrazones … Continue reading

Posted in Computational chemistry, Eugenia Marqués-López, Henry, Organocatalysis, Publication, Raquel P. Herrera | Tagged , , , , , , , , , , | Leave a comment

First fruit of a very interesting collaboration…

… with Dr. Santiago Uriel. Thank you and congratulations! Simple iodoalkyne-based organocatalysts for the activation of carbonyl compounds, Alegre-Requena, J. V.; Valero-Tena, A.; Sonsona, I. G.; Uriel, S.; Herrera, R. P. Org. Biomol. Chem. 2020, DOI: 10.1039/c9ob02688f Abstract. A novel … Continue reading

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A little tribute to (THIO)UREAS. Improving their organocatalytic activity…

Hydrogen bonding and Internal or External Lewis or Brønsted Acid Assisted (Thio)urea Catalysts, Gimeno, M. C.; Herrera, R. P. Eur. J. Org. Chem. 10.1002/ejoc.201901344 Abstract. The obtainment of more active organocatalysts has promoted the search for new modes of activation … Continue reading

Posted in Hydrogen-bonding, Organocatalysis, Publication, Raquel P. Herrera, Review, Thiourea, Urea | Tagged , , , , , , , , , , | Leave a comment

Luca and Raquel: old friends together after 15 years!

Last Friday, March 8th, Dr. Luca Bernardi (University of Bologna) visited Zaragoza and gave us a wonderful talk as a present, about “Asymmetric Organocatalysis: Principles and Applications“. Thanks a lot, Luca!

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Celebrating the publication of a new article!

First Organocatalytic Asymmetric Synthesis of 1-Benzamido-1,4-Dihydropyridine Derivatives,  Auria-Luna, F.; Marqués-López, E.; Herrera, R. P.  Molecules 2018, 23(10), 2692. https://doi.org/10.3390/molecules23102692. Special Issue “Stereogenic Centers“ Abstract. Preliminary results concerning the first asymmetric synthesis of highly functionalized 1-benzamido-1,4-dihydropyridine derivatives via the reaction of hydrazones with alkylidenemalononitriles … Continue reading

Posted in Dihydropyridines, Eugenia Marqués-López, Heterocycle, Organic chemistry, Organocatalysis, Publication, Raquel P. Herrera, Research | Tagged , , , , , , , , , , | Leave a comment

Urea Activation by an External Brønsted Acid: Breaking Self-Association and Tuning Catalytic Performance

Urea Activation by an External Brønsted Acid: Breaking Self-Association and Tuning Catalytic Performance Isaac G. Sonsona, Eugenia Marqués-López, Marleen Häring, David Díaz Díaz  and Raquel P. Herrera Catalysts 2018, 8(8), 305; https://doi.org/10.3390/catal8080305 Abstract: In this work, we hypothesize that Brønsted acids can activate urea-based catalysts by diminishing its … Continue reading

Posted in Collaboration, Eugenia Marqués-López, Gel, Hydrogen-bonding, Organocatalysis, Publication, Raquel P. Herrera, Urea | Tagged , , , , , , , , , , , | Leave a comment

Sandra got already her BSc degree!

Last wednesday, Sandra presented her Bachelor thesis entitled “Synthesis and applications of heterocycles of interest”. She did it excellent. Congratulations!

Posted in B.Sc. Thesis, Defense, Heterocycle, Organocatalysis, Raquel P. Herrera, Thiourea | Tagged , , , , , | Leave a comment

Juanvi joined the UPPA-UPV / EHU Transboundary Doctorials

Juanvi has been in Arantzazu (Gipuzkoa), from October 16th to 19th working with other PhD students in the “Doctoriales transfronterizos UPPA-UPV/EHU” (UPPA-UPV / EHU Transboundary Doctorials), organized by the Master’s and Doctorate School of the UPV / EHU (MDe), in collaboration with the … Continue reading

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