Category Archives: Organocatalysis

A little tribute to (THIO)UREAS. Improving their organocatalytic activity…

Posted on November 6, 2019 by

Hydrogen bonding and Internal or External Lewis or Brønsted Acid Assisted (Thio)urea Catalysts, Gimeno, M. C.; Herrera, R. P. Eur. J. Org. Chem. 10.1002/ejoc.201901344 Abstract. The obtainment of more active organocatalysts has promoted the search for new modes of activation … Continue reading →

Posted in Hydrogen-bonding, Organocatalysis, Publication, Raquel P. Herrera, Review, Thiourea, Urea | Tagged , , , , , , , , , , | Leave a comment

Luca and Raquel: old friends together after 15 years!

Posted on March 15, 2019 by

Last Friday, March 8th, Dr. Luca Bernardi (University of Bologna) visited Zaragoza and gave us a wonderful talk as a present, about “Asymmetric Organocatalysis: Principles and Applications“. Thanks a lot, Luca!

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Celebrating the publication of a new article!

Posted on October 19, 2018 by

First Organocatalytic Asymmetric Synthesis of 1-Benzamido-1,4-Dihydropyridine Derivatives,  Auria-Luna, F.; Marqués-López, E.; Herrera, R. P.  Molecules 2018, 23(10), 2692. https://doi.org/10.3390/molecules23102692. Special Issue “Stereogenic Centers“ Abstract. Preliminary results concerning the first asymmetric synthesis of highly functionalized 1-benzamido-1,4-dihydropyridine derivatives via the reaction of hydrazones with alkylidenemalononitriles … Continue reading →

Posted in Dihydropyridines, Eugenia Marqués-López, Heterocycle, Organic chemistry, Organocatalysis, Publication, Raquel P. Herrera, Research | Tagged , , , , , , , , , , | Leave a comment

Urea Activation by an External Brønsted Acid: Breaking Self-Association and Tuning Catalytic Performance

Posted on September 4, 2018 by

Urea Activation by an External Brønsted Acid: Breaking Self-Association and Tuning Catalytic Performance Isaac G. Sonsona, Eugenia Marqués-López, Marleen Häring, David Díaz Díaz  and Raquel P. Herrera Catalysts 2018, 8(8), 305; https://doi.org/10.3390/catal8080305 Abstract: In this work, we hypothesize that Brønsted acids can activate urea-based catalysts by diminishing its … Continue reading →

Posted in Collaboration, Eugenia Marqués-López, Gel, Hydrogen-bonding, Organocatalysis, Publication, Raquel P. Herrera, Urea | Tagged , , , , , , , , , , , | Leave a comment

Sandra got already her BSc degree!

Posted on July 13, 2018 by

Last wednesday, Sandra presented her Bachelor thesis entitled “Synthesis and applications of heterocycles of interest”. She did it excellent. Congratulations!

Posted in B.Sc. Thesis, Defense, Heterocycle, Organocatalysis, Raquel P. Herrera, Thiourea | Tagged , , , , , | Leave a comment

Juanvi joined the UPPA-UPV / EHU Transboundary Doctorials

Posted on November 1, 2017 by

Juanvi has been in Arantzazu (Gipuzkoa), from October 16th to 19th working with other PhD students in the “Doctoriales transfronterizos UPPA-UPV/EHU” (UPPA-UPV / EHU Transboundary Doctorials), organized by the Master’s and Doctorate School of the UPV / EHU (MDe), in collaboration with the … Continue reading →

Posted in Congress, Doctorate, Organocatalysis, Squaramide | Tagged , , , , , , , , | Leave a comment

Just accepted! New article about making more efficient enatioselective organocatalytic reactions

Posted on October 27, 2017 by

Juanvi has worked hard in this project and now the first results have just come out. The central idea is to generate in situ, the carbonyl compound, via oxidation of an alcohol, which is involved in a subsequent asymmetric organocatalytic … Continue reading →

Posted in Catalysis, Henry, Hydrogen-bonding, Organocatalysis, Publication, Raquel P. Herrera, Research, Squaramide | Tagged , , , , , , , , , , , | Leave a comment

Deepening the knowledge of Henry reaction catalyzed by squaramides

Posted on August 19, 2017 by

We have just published very interesting studies about the Henry reaction, which allow understanding more in detail the activation of the substrates by a very effective squaramide. Enjoy them… Congratulations Juanvi! “Push−Pull π+/π−” (PPππ) Systems in Catalysis, Alegre Requena J. … Continue reading →

Posted in Computational chemistry, Eugenia Marqués-López, Organocatalysis, Publication, Raquel P. Herrera, Research, Squaramide | Tagged , , , , , , , , , | Leave a comment

Celebrating our last publication!

Posted on June 7, 2017 by

Asymmetric Organocatalytic Synthesis of Substituted Chiral 1,4-Dihydropyridine Derivatives. Fernando Auria-Luna, Eugenia Marqués-López, M. Concepción Gimeno, Roghayeh Heiran, Somayeh Mohammadi, and Raquel P. Herrera, J. Org. Chem. 2017, 82, 5516–5523. Abstract. The first cinchona-alkaloid-organocatalyzed enantioselective synthesis of chiral 1,4-dihydropyridine derivatives is described. Bis-cinchona catalyst 3b … Continue reading →

Posted in Cinchona, Dihydropyridines, Eugenia Marqués-López, Organocatalysis, Publication, Raquel P. Herrera, Research | Tagged , , , , , , , , , | Leave a comment

Organocatalytic methods collection to obtain chiral 1,4-DHPs, just accepted in Adv. Synth. Catal.

Posted on May 3, 2017 by

Organocatalytic enantioselective synthesis of 1,4-dihydropyridines, Auria-Luna, F.; Marqués-López, E.; Herrera, R. P.  Adv. Synth. Catal. 2017, DOI 10.1002/adsc.201700300 Abstract. This review aims to bring light upon a very interesting group of compounds, the 1,4-dihydropyridines (1,4-DHPs). These structures are well-known pharmacophores, used for many years … Continue reading →

Posted in Dihydropyridines, Eugenia Marqués-López, Organocatalysis, Publication, Raquel P. Herrera, Review | Tagged , , , , , , , , , , | Leave a comment