Tag Archives: Cancer

New work on DHPs, just available online!

Congratulations to everyone, in special to Sandra! Well done! 1-Benzamido-1,4-dihydropyridine derivatives as anticancer agents: in vitro and in vivo assays, Ardevines, S.; Auria-Luna, F.; Romanos, E.; Fernández-Moreira, V.; Benedi, A.; Gimeno, M. C.; Marzo, I.; Marqués-López, E.; Herrera, R. P. Arab. J. Chem. 2022, 104514. https://doi.org/10.1016/j.arabjc.2022.104514. Abstract. … Continue reading

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HOCA present at the race against cancer

Last June 19th, Fanny and Sandra participated at the “VII Marcha contra el cáncer en Zaragoza”. Proud of our girls!

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Congratulations Guille for the first of many scientific articles!

Synthesis of New Thiourea-Metal Complexes with Promising Anticancer Properties, Canudo-Barreras, G.; Ortego, L.; Izaga, A.; Marzo, I.; Herrera, R. P.; Gimeno, M. C. Molecules 2021, 26(22), 6891. https://doi.org/10.3390/molecules26226891. Abstract. In this work, two thiourea ligands bearing a phosphine group in … Continue reading

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DHPs in 6th International Electronic Conference on Medicinal Chemistry (Nov 2020)

Novel ureido-dihydropyridine scaffolds as theranostic agents F. Auria-Luna,* S. Ardevines, E. Marqués-López, E. Romanos, V. Fernández-Moreira, M. C. Gimeno, I. Marzo, R. P. Herrera 10.3390/ECMC2020-07419 (registering DOI) Abstract: The potential as anticancer agents of 1,4-dihydropyridines (1,4-DHPs) and their pioneering urea … Continue reading

Posted in Biological activity, Cancer, Collaboration, Conference, Congress, Dihydropyridines, Heterocycle, Publication, Raquel P. Herrera | Tagged , , , , , , , , , , , , , , , , , | Leave a comment

Further knowledge on DHP just published!

We did it again! Congratulations guys! Novel ureido-dihydropyridine scaffolds as theranostic agents, Auria-Luna, F.; Marqués-López, E.; Romanos, E.; Fernández-Moreira, V.; Gimeno, M. C.; Marzo, I.; Herrera, R. P. Bioorg. Chem. 2020, https://doi.org/10.1016/j.bioorg.2020.104364. Abstract. In this work, the synthesis of interesting urea derivatives 5 based on … Continue reading

Posted in Dihydropyridines, Eugenia Marqués-López, Heterocycle, Publication, Raquel P. Herrera | Tagged , , , , , , , , , , | Leave a comment

Closing a period of life opens you new horizons. Good luck!

Sara and Pablo, the youngest HOCA members, did their final exams last wenesday (september, 25th) and now they are ready to get their B.Sc. Diplomes. Organic Privileged Scaffolds with Anticancer Activity: Synthesis through Organocatalytic Procedures. Sara Gil. Design and synthesis … Continue reading

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Indole and isatin derivatives with Au(I): Highly cytotoxic metallic species

Bioactive and luminescent indole and isatin based gold(I) derivatives, Fernández-Moreira, V.; Val-Campillo, C.; Ospino, I.; Herrera, R. P.; Marzo, I.; Laguna, A.; Gimeno, M. C. Dalton Trans. 2019. DOI: 10.1039/C8DT00298C Abstract. A series of luminescent monometallic [AuL(PPh3)] (1-3) and bimetallic [Au2(µ-dppe)L2] (4, … Continue reading

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Enjoy reading a new review about anticancer properties of gold complexes

Anticancer Properties of Gold Complexes with Biologically Relevant Ligands, Fernández-Moreira, V.; Herrera, R. P.; Gimeno, M. C. Pure Appl. Chem. 2018, DOI: https://doi.org/10.1515/pac-2018-0901 Abstract. The present review highlights our findings in the field of antitumor gold complexes bearing biologically relevant molecules, such as DNA-bases, amino acids … Continue reading

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