Tag Archives: Dihydropyridines

Celebrating our last publication!

Asymmetric Organocatalytic Synthesis of Substituted Chiral 1,4-Dihydropyridine Derivatives. Fernando Auria-Luna, Eugenia Marqués-López, M. Concepción Gimeno, Roghayeh Heiran, Somayeh Mohammadi, and Raquel P. Herrera, J. Org. Chem. 2017, 82, 5516–5523. Abstract. The first cinchona-alkaloid-organocatalyzed enantioselective synthesis of chiral 1,4-dihydropyridine derivatives is described. Bis-cinchona catalyst 3b … Continue reading

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Organocatalytic methods collection to obtain chiral 1,4-DHPs, just accepted in Adv. Synth. Catal.

Organocatalytic enantioselective synthesis of 1,4-dihydropyridines, Auria-Luna, F.; Marqués-López, E.; Herrera, R. P.  Adv. Synth. Catal. 2017, DOI 10.1002/adsc.201700300 Abstract. This review aims to bring light upon a very interesting group of compounds, the 1,4-dihydropyridines (1,4-DHPs). These structures are well-known pharmacophores, used for many years … Continue reading

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HOCA to publish a New Synthesis of Chiral 2-Oxospiro-[indole-3,4′- (1′,4′-dihydropyridines)]

We are interested in the enantioselective synthesis of highly functionalized molecules with biological activity. In this frame, we have just published “a preliminary study” in the development of a “New Organocatalytic Asymmetric Synthesis of Highly Substituted Chiral 2-Oxo Spiro-[indole-3,4′- (1′,4′-dihydropyridine)] … Continue reading

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