Category Archives: Collaboration

DHPs in 6th International Electronic Conference on Medicinal Chemistry (Nov 2020)

Novel ureido-dihydropyridine scaffolds as theranostic agents F. Auria-Luna,* S. Ardevines, E. Marqués-López, E. Romanos, V. Fernández-Moreira, M. C. Gimeno, I. Marzo, R. P. Herrera 10.3390/ECMC2020-07419 (registering DOI) Abstract: The potential as anticancer agents of 1,4-dihydropyridines (1,4-DHPs) and their pioneering urea … Continue reading

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Overview on asymmetric fluorination reactions by means of ORGANOCATALYSIS

Asymmetric Fluorination Reactions Promoted by Chiral Hydrogen‐Bonding‐Based Organocatalysts, Auria-Luna, F.; Mohammadi, S.; Divar, M.; Gimeno, M. C.; Herrera, R. P. Adv. Synth. Catal. 2020, https://doi.org/10.1002/adsc.202000848 VIP Abstract. Fluorinated compounds can exhibit interesting biological properties. The importance of these species has made … Continue reading

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Congrats for this new article!

Sulfonamide as amide isostere for fine-tuning the gelation properties of physical gels, Alegre-Requena, J. V.; Grijalvo, S.; Sampedro, D.;  Mayr, J.;  Saldías, C.; Marrero-Tellado, J. J.; Eritja, R.; Herrera, R. P.; Díaz, D. D. RSC Adv. 2020, 10, 11481-11492. Abstract. … Continue reading

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First fruit of a very interesting collaboration…

… with Dr. Santiago Uriel. Thank you and congratulations! Simple iodoalkyne-based organocatalysts for the activation of carbonyl compounds, Alegre-Requena, J. V.; Valero-Tena, A.; Sonsona, I. G.; Uriel, S.; Herrera, R. P. Org. Biomol. Chem. 2020, DOI: 10.1039/c9ob02688f Abstract. A novel … Continue reading

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Hot paper Chem. Eur. J. – Congratulations!

Thiolate Bridged Gold(I)–NHC Catalysts: New Approach for Catalyst Design and its Application to Trapping Catalytic Intermediates Renso Visbal, Raquel P. Herrera* and M. Concepción Gimeno* Chem. Eur. J. 2019, 25, 15837–15845. More info (in Spanish).

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Synergistic catalysis as well as synergistic teamwork

Proline bulky substituents consecutively act as steric hindrances and directing groups in a Michael/Conia-ene cascade reaction under synergistic catalysis, Putatunda, S.; Alegre-Requena, J. V.; Meazza, M.; Franc, M.; Rohaľová, D.; Vemuri, P.; Císařová, I.; Herrera, R. P.; Rios, R.; Veselý, … Continue reading

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Indole and isatin derivatives with Au(I): Highly cytotoxic metallic species

Bioactive and luminescent indole and isatin based gold(I) derivatives, Fernández-Moreira, V.; Val-Campillo, C.; Ospino, I.; Herrera, R. P.; Marzo, I.; Laguna, A.; Gimeno, M. C. Dalton Trans. 2019. DOI: 10.1039/C8DT00298C Abstract. A series of luminescent monometallic [AuL(PPh3)] (1-3) and bimetallic [Au2(µ-dppe)L2] (4, … Continue reading

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Enjoy reading a new review about anticancer properties of gold complexes

Anticancer Properties of Gold Complexes with Biologically Relevant Ligands, Fernández-Moreira, V.; Herrera, R. P.; Gimeno, M. C. Pure Appl. Chem. 2018, DOI: https://doi.org/10.1515/pac-2018-0901 Abstract. The present review highlights our findings in the field of antitumor gold complexes bearing biologically relevant molecules, such as DNA-bases, amino acids … Continue reading

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Gold Catalyzed Multicomponent Reactions beyond A3Coupling

Gold Catalyzed Multicomponent Reactions beyond A3Coupling Renso Visbal, Sara Graus, Raquel P. Herrera, M. Concepción Gimeno Molecules 2018, 23(9), 2255. https://doi.org/10.3390/molecules23092255 Abstract: The preparation of complex architectures has inspired the search for new methods and new processes in organic synthesis. Multicomponent reactions have become an … Continue reading

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Efficient Gold(I) Acyclic Diaminocarbenes for the Synthesis of Propargylamines and Indolizines

Efficient Gold(I) Acyclic Diaminocarbenes for the Synthesis of Propargylamines and Indolizines Mélanie Aliaga-Lavrijsen, Raquel P. Herrera, M. Dolores Villacampa, and M. Concepción Gimeno ACS Omega, 2018, 3, 9805–9813. Abstract: Mononuclear gold(I) acyclic diaminocarbenes (ADCs) were prepared by the reaction of 1,2-cyclohexanediamine with the corresponding isocyanide complexes … Continue reading

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