Category Archives: Thiourea

A synergistic couple of catalysts

A new article has just been accepted. Congratulations! Gold(I) mediated thiourea organocatalyst activation: A synergic effect for asymmetric catalysis. Anabel Izaga, Raquel P. Herrera, M. Concepción Gimeno, ChemCatChem, 2017, 10.1002/cctc.201601527. Abstract. Several group 11 metal complexes with chiral thiourea organocatalysts have … Continue reading

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A further step towards understanding one of our best “friends”: aminoindanol-based thiourea

Hydrogen bonding networks in chiral thiourea organocatalysts. Evidence on the importance of the aminoindanol moiety. Gimeno, M. C.; Herrera, R. P. Cryst. Growth Des., 2016, 16, 5091–5099. Abstract. The crystal structures of four chiral thioureas, which are normally used as organocatalysts, are reported by … Continue reading

Posted in Collaboration, Hydrogen-bonding, Organocatalysis, Publication, Raquel P. Herrera, Research, Thiourea | Tagged , , , , , , , , | Leave a comment

Wanna know what happens if you consider MOFs and HBC together? Take a look to this highlight, just published in CrystEngComm

The highlight entitled “Metal-organic frameworks (MOFs) bring new life to hydrogen-bonding organocatalysts in confined spaces” has just been published at CrystEngComm. In this work, together with Prof. David Díaz (Universität Regensburg), we have compiled and studied the literature which involves the intriguing idea of … Continue reading

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HOCA to publish a New Synthesis of Chiral 2-Oxospiro-[indole-3,4′- (1′,4′-dihydropyridines)]

We are interested in the enantioselective synthesis of highly functionalized molecules with biological activity. In this frame, we have just published “a preliminary study” in the development of a “New Organocatalytic Asymmetric Synthesis of Highly Substituted Chiral 2-Oxo Spiro-[indole-3,4′- (1′,4′-dihydropyridine)] … Continue reading

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HOCA publishes a review about the synthesis of chromenes

We have compiled and reviewed the recent literature about “Enantioselective Organocatalyzed Synthesis of 2-Amino-3-cyano-4H-chromene Derivatives” and the resulting article has been just published in Symmetry in the frame of its Special Issue dedicated to “Asymmetric Organocatalysis”. Isaac G. Sonsona, Eugenia Marqués-López  and Raquel P. Herrera. Symmetry 2015, … Continue reading

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HOCA publishes a new method of addition of indoles to aliphatic β,γ-unsaturated α-ketoesters catalyzed by a chiral thiourea

“Thiourea-Catalyzed Addition of Indoles to Aliphatic β,γ-Unsaturated α-Ketoesters” by Verónica Juste-Navarro, Eugenia Marqués-López and Raquel P. Herrera has been published in Asian Journal of Organic Chemistry. DOI: 10.1002/ajoc.201500154 Abstract: The first thiourea-catalyzed addition reaction of indoles to aliphatic β,γ-unsaturated α-ketoesters has been developed. … Continue reading

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