Category Archives: Dihydropyridines

DHPs in 6th International Electronic Conference on Medicinal Chemistry (Nov 2020)

Novel ureido-dihydropyridine scaffolds as theranostic agents F. Auria-Luna,* S. Ardevines, E. Marqués-López, E. Romanos, V. Fernández-Moreira, M. C. Gimeno, I. Marzo, R. P. Herrera 10.3390/ECMC2020-07419 (registering DOI) Abstract: The potential as anticancer agents of 1,4-dihydropyridines (1,4-DHPs) and their pioneering urea … Continue reading

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Further knowledge on DHP just published!

We did it again! Congratulations guys! Novel ureido-dihydropyridine scaffolds as theranostic agents, Auria-Luna, F.; Marqués-López, E.; Romanos, E.; Fernández-Moreira, V.; Gimeno, M. C.; Marzo, I.; Herrera, R. P. Bioorg. Chem. 2020, https://doi.org/10.1016/j.bioorg.2020.104364. Abstract. In this work, the synthesis of interesting urea derivatives 5 based on … Continue reading

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Last results on heterocycles biological properties studies have been recently spread online

I Multifunctional Metallodrugs in Diagnosis and Therapy Meeting MultiMetDrugs (27 de Julio) In the frame of the 1st Group Meeting of the Spanish network MultiMetDrugs coordinated by Prof. Gimeno’s group, Fer faced the prelude to his doctoral thesis defense presenting … Continue reading

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Working and relaxing…

… both are compatible and necessary to enjoy life 😉  

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Fer participated in the II Doctoral Conference of the Organic Chemistry Doctoral Program of the UZ

Last monday, may 27th, Fer presented very successfully, the most recent results of his PhD projects in the II Jornada Doctoral, celebrated in the Faculty of Sciences of our University. Congratulations!

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The young chemists and physicists of Aragon told us yesterday their work in the Faculty of Sciences

The 8th Young Aragonese Researchers Meeting took place yesterday (November 22th) in the Faculty of Sciences (Zaragoza). 8ª Jornada de Jóvenes Investigadores (Química y Física) de Aragón. (8ª JJIQFA) Isaac, Anabel and Fernando successfully presented part of their Doctoral Thesis work. Congratulations! … Continue reading

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Celebrating the publication of a new article!

First Organocatalytic Asymmetric Synthesis of 1-Benzamido-1,4-Dihydropyridine Derivatives,  Auria-Luna, F.; Marqués-López, E.; Herrera, R. P.  Molecules 2018, 23(10), 2692. https://doi.org/10.3390/molecules23102692. Special Issue “Stereogenic Centers“ Abstract. Preliminary results concerning the first asymmetric synthesis of highly functionalized 1-benzamido-1,4-dihydropyridine derivatives via the reaction of hydrazones with alkylidenemalononitriles … Continue reading

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Celebrating our last publication!

Asymmetric Organocatalytic Synthesis of Substituted Chiral 1,4-Dihydropyridine Derivatives. Fernando Auria-Luna, Eugenia Marqués-López, M. Concepción Gimeno, Roghayeh Heiran, Somayeh Mohammadi, and Raquel P. Herrera, J. Org. Chem. 2017, 82, 5516–5523. Abstract. The first cinchona-alkaloid-organocatalyzed enantioselective synthesis of chiral 1,4-dihydropyridine derivatives is described. Bis-cinchona catalyst 3b … Continue reading

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Organocatalytic methods collection to obtain chiral 1,4-DHPs, just accepted in Adv. Synth. Catal.

Organocatalytic enantioselective synthesis of 1,4-dihydropyridines, Auria-Luna, F.; Marqués-López, E.; Herrera, R. P.  Adv. Synth. Catal. 2017, DOI 10.1002/adsc.201700300 Abstract. This review aims to bring light upon a very interesting group of compounds, the 1,4-dihydropyridines (1,4-DHPs). These structures are well-known pharmacophores, used for many years … Continue reading

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