Category Archives: Heterocycle

DHPs in 6th International Electronic Conference on Medicinal Chemistry (Nov 2020)

Novel ureido-dihydropyridine scaffolds as theranostic agents F. Auria-Luna,* S. Ardevines, E. Marqués-López, E. Romanos, V. Fernández-Moreira, M. C. Gimeno, I. Marzo, R. P. Herrera 10.3390/ECMC2020-07419 (registering DOI) Abstract: The potential as anticancer agents of 1,4-dihydropyridines (1,4-DHPs) and their pioneering urea … Continue reading

Posted in Biological activity, Cancer, Collaboration, Conference, Congress, Dihydropyridines, Heterocycle, Publication, Raquel P. Herrera | Tagged , , , , , , , , , , , , , , , , , | Leave a comment

Further knowledge on DHP just published!

We did it again! Congratulations guys! Novel ureido-dihydropyridine scaffolds as theranostic agents, Auria-Luna, F.; Marqués-López, E.; Romanos, E.; Fernández-Moreira, V.; Gimeno, M. C.; Marzo, I.; Herrera, R. P. Bioorg. Chem. 2020, https://doi.org/10.1016/j.bioorg.2020.104364. Abstract. In this work, the synthesis of interesting urea derivatives 5 based on … Continue reading

Posted in Dihydropyridines, Eugenia Marqués-López, Heterocycle, Publication, Raquel P. Herrera | Tagged , , , , , , , , , , | Leave a comment

Last results on heterocycles biological properties studies have been recently spread online

I Multifunctional Metallodrugs in Diagnosis and Therapy Meeting MultiMetDrugs (27 de Julio) In the frame of the 1st Group Meeting of the Spanish network MultiMetDrugs coordinated by Prof. Gimeno’s group, Fer faced the prelude to his doctoral thesis defense presenting … Continue reading

Posted in Dihydropyridines, DNA, Fluorescence, Heterocycle, Meeting, Pyrans, Raquel P. Herrera | Tagged , , , , , , | Leave a comment

HOCA initiation in DNA binding studies of compounds obtained through green methods

Ultrasound-assisted multicomponent synthesis of 4H-pyrans in water and DNA binding studies, Auria-Luna, F.; Fernández-Moreira, V.; Marqués-López, E.; Gimeno, M. C.; Herrera, R. P. Sci. Rep. 2020 , 10, 11594. https://doi.org/10.1038/s41598-020-68076-1 Abstract. A simple approach to synthesize new highly substituted 4H-pyran … Continue reading

Posted in DNA, Heterocycle, Multicomponent reaction, Organocatalysis, Publication, Pyrans, Research, Synthesis | Tagged , , , , , , , , , , , , , , , | Leave a comment

Celebrating the publication of a new article!

First Organocatalytic Asymmetric Synthesis of 1-Benzamido-1,4-Dihydropyridine Derivatives,  Auria-Luna, F.; Marqués-López, E.; Herrera, R. P.  Molecules 2018, 23(10), 2692. https://doi.org/10.3390/molecules23102692. Special Issue “Stereogenic Centers“ Abstract. Preliminary results concerning the first asymmetric synthesis of highly functionalized 1-benzamido-1,4-dihydropyridine derivatives via the reaction of hydrazones with alkylidenemalononitriles … Continue reading

Posted in Dihydropyridines, Eugenia Marqués-López, Heterocycle, Organic chemistry, Organocatalysis, Publication, Raquel P. Herrera, Research | Tagged , , , , , , , , , , | Leave a comment

Some HOCA members attend to GEQO in Zaragoza

These days (5th to 7th September 2018)  XXXVI CONGRESS OF THE ORGANOMETALLIC CHEMISTRY GROUP (GEQO) is taking place in Zaragoza. HOCA is involved in its organization since Raquel is member of the Organaizing Committee. Is going to be a great success!!  Congratullations 😉 We … Continue reading

Posted in Congress, Eugenia Marqués-López, Heterocycle, Multicomponent reaction, Raquel P. Herrera, Research, Synthesis | Tagged , , , , , , | Leave a comment

Sandra got already her BSc degree!

Last wednesday, Sandra presented her Bachelor thesis entitled “Synthesis and applications of heterocycles of interest”. She did it excellent. Congratulations!

Posted in B.Sc. Thesis, Defense, Heterocycle, Organocatalysis, Raquel P. Herrera, Thiourea | Tagged , , , , , | Leave a comment

HOCA to publish a New Synthesis of Chiral 2-Oxospiro-[indole-3,4′- (1′,4′-dihydropyridines)]

We are interested in the enantioselective synthesis of highly functionalized molecules with biological activity. In this frame, we have just published “a preliminary study” in the development of a “New Organocatalytic Asymmetric Synthesis of Highly Substituted Chiral 2-Oxo Spiro-[indole-3,4′- (1′,4′-dihydropyridine)] … Continue reading

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HOCA publishes a review about the synthesis of chromenes

We have compiled and reviewed the recent literature about “Enantioselective Organocatalyzed Synthesis of 2-Amino-3-cyano-4H-chromene Derivatives” and the resulting article has been just published in Symmetry in the frame of its Special Issue dedicated to “Asymmetric Organocatalysis”. Isaac G. Sonsona, Eugenia Marqués-López  and Raquel P. Herrera. Symmetry 2015, … Continue reading

Posted in Chromene, Heterocycle, Organocatalysis, Publication, Synthesis, Thiourea | Tagged , , , , , , , , , | Leave a comment