Category Archives: Research

New collaborative study just published in ChemCatChem

Posted on October 31, 2025 by mmaamarq

Congrats, especially to Sandra and thank you to Israel and his team! Exploring the Role of Halogen Bond Donors in the Thiourea-Catalyzed Friedel–Crafts Alkylation Reaction, Ardevines, S.; González-Pinardo, D.; Fernández, I.; Marqués-López, E.; Herrera, R. P.; Chem. Cat. Chem. 2025. … Continue reading →

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Recent HOCA contribution to the field of Deep Eutectic Solvents

Posted on February 16, 2024 by mmaamarq

L-Proline-based deep eutectic solvents as green and enantioselective organocatalyst/media for aldol reaction, Zárate-Rondán, S.; Trujillo-Rodríguez, M. J.; Gimeno, M. C.; Herrera, R. P. J. Mol. Liq. 2024, 396, 123971. DOI: 10.1016/j.molliq.2024.123971. Abstract The use of chiral deep eutectic solvents (DESs) … Continue reading →

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Smooth synthesis of chromenylphosphonates, early view

Posted on August 17, 2023 by mmaamarq

Asymmetric Organocatalyzed Phospha-Michael Addition for the Direct Synthesis of Biologically Active Chromenylphosphonates,*   Marqués-López, E.; Sonsona, I. G.; Garcés-Marín, M.; Gimeno, M. C.; Herrera, R. P. Adv. Synth. Catal. 2023, 365. DOI: 10.1002/adsc.202300563. *A previous version of this manuscript has been deposited … Continue reading →

Posted in Chromene, Eugenia Marqués-López, Heterocycle, Organocatalysis, Publication, Raquel P. Herrera, Research | Tagged , , , , , , , , , , , | Leave a comment

A new article just come out!

Posted on March 13, 2023 by mmaamarq

Catalysis-free synthesis of thiazolidine–thiourea ligands for metal coordination (Au and Ag) and preliminary cytotoxic studies, Salvador-Gil, D.; Herrera, R. P.; Gimeno, M. C.  Dalton Trans. 2023. DOI: https://doi.org/10.1039/D3DT00079F. Abstract. The reaction of propargylamines with isothiocyanates results in the selective formation of … Continue reading →

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New work on DHPs, just available online!

Posted on December 13, 2022 by mmaamarq

Congratulations to everyone, in special to Sandra! Well done! 1-Benzamido-1,4-dihydropyridine derivatives as anticancer agents: in vitro and in vivo assays, Ardevines, S.; Auria-Luna, F.; Romanos, E.; Fernández-Moreira, V.; Benedi, A.; Gimeno, M. C.; Marzo, I.; Marqués-López, E.; Herrera, R. P. Arab. J. Chem. 2022, 104514. https://doi.org/10.1016/j.arabjc.2022.104514. Abstract. … Continue reading →

Posted in Cancer, Dihydropyridines, Publication, Research | Tagged , , , , , , , , , , , , , , , | Leave a comment

First results for HOCA combining organo and biocatalysis!!

Posted on August 31, 2022 by mmaamarq

Congratulations Christian, Juan and Raquel! Stereoselective Three-Step One-Pot Cascade Combining Amino- and Biocatalysis to Access Chiral Υ-Nitro Alcohols, Ascaso-Alegre, C.; Herrera, R. P.; Mangas-Sanchez, J. Angew. Chem. Int. Ed. 2022. https://doi.org/10.1002/anie.202209159. Abstract. The combination of small molecule catalysis and enzyme catalysis represents an underexploited … Continue reading →

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Marta very concentrated with her experiments!

Posted on May 20, 2022 by mmaamarq

Bio essays require a lot of patience and rigor. Cheer up!

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Congratulations Guille for the first of many scientific articles!

Posted on November 18, 2021 by mmaamarq

Synthesis of New Thiourea-Metal Complexes with Promising Anticancer Properties, Canudo-Barreras, G.; Ortego, L.; Izaga, A.; Marzo, I.; Herrera, R. P.; Gimeno, M. C. Molecules 2021, 26(22), 6891. https://doi.org/10.3390/molecules26226891. Abstract. In this work, two thiourea ligands bearing a phosphine group in … Continue reading →

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HOCA initiation in DNA binding studies of compounds obtained through green methods

Posted on July 15, 2020 by mmaamarq

Ultrasound-assisted multicomponent synthesis of 4H-pyrans in water and DNA binding studies, Auria-Luna, F.; Fernández-Moreira, V.; Marqués-López, E.; Gimeno, M. C.; Herrera, R. P. Sci. Rep. 2020 , 10, 11594. https://doi.org/10.1038/s41598-020-68076-1 Abstract. A simple approach to synthesize new highly substituted 4H-pyran … Continue reading →

Posted in DNA, Heterocycle, Multicomponent reaction, Organocatalysis, Publication, Pyrans, Research, Synthesis | Tagged , , , , , , , , , , , , , , , | Leave a comment

The results of a new collaboration with University of Gabes

Posted on October 25, 2019 by mmaamarq

Synthesis, structural determination and catalytic study of a new 2-D chloro-substituted zinc phosphate, (C8N2H20)[ZnCl(PO3(OH))]2, Rayes, A.; Herrera, R. P.; Moncer, M.; Ara, I.; Calestani, G.; Ayed, B.; Mezzadri, F. J. Mol. Struct. 2019, https://doi.org/10.1016/j.molstruc.2019.127216 Abstract. A novel chloro-substituted zinc-phosphate, (C8N2H20)[ZnCl(PO3(OH)]2, … Continue reading →

Posted in Publication, Raquel P. Herrera, Research | Tagged , , , , , , , , , , , , , , | Leave a comment