Juanvi was selected by the University of Zaragoza to participate in the V Jornadas Doctorales G-9 (Palma de Mallorca, del 8 al 10 de febrero de 2017). He presented there, his doctorate topic: SQUARAMIDES.
Juanvi giving his talk about SQUARAMIDES in the “V Jornadas Doctorales G-9”.
Organocatalytic Hydrophosphonylation Reaction of Carbonyl Groups. Herrera, R. P. Chem. Rec. 2017, DOI: 10.1002/tcr.201600129.
Abstract. This revision is covering the limited examples reported for a pivotal strategy in the formation of C−P bonds such as the asymmetric organocatalytic hydrophosphonylation of carbonyl groups (Pudovik reaction). The scope and limitations, and the proposed mechanisms for the scarce different possibilities of asymmetric induction are also shown. The recent evolution and future trends of this undeveloped approach are commented.
Juanvi, has recently attended to the 8th European Symposium on Computing π-Conjugated Compounds, celebrated in Malaga from Jan. 27th to 28th.
There, he presented an oral communication about the most recent results of his doctoral thesis in the field of computational studies of organocatalytic reactions, entitled “Studying Computationally Anion-π Interactions for the First Time in Asymmetric Catalysis: Squaramide-Catalyzed Henry Reaction”
For sure, he learnt a lot and enjoyed this wonderful city.
Well done!
Maru is now the Assistant Director for International Affairs at the Technological College of Huesca, taking part of the new direction team.
Congratulations!
A new article has just been accepted. Congratulations!
Gold(I) mediated thiourea organocatalyst activation: A synergic effect for asymmetric catalysis. Anabel Izaga, Raquel P. Herrera, M. Concepción Gimeno, ChemCatChem, 2017, 10.1002/cctc.201601527.
Abstract. Several group 11 metal complexes with chiral thiourea organocatalysts have been prepared and tested as organocatalysts. The promising results on the influence of metal assisted thiourea organocatalysts in the asymmetric Friedel-Crafts alkylation of indole with nitrostyrene are described. Better results with the metal complexes have been achieved because of the cooperative effects between the chiral thiourea and the metal. The synergic effect between both species is higher than the effect promoted by each one separately, especially for gold(I). These outcomes are attributed to a pioneering gold(I) activation of the thiourea catalysts, affording a more acidic and rigid catalytic complex than that provided by the thiourea alone. Furthermore, the use of the gold-thiourea organocatalyst allows reducing the catalyst loading to 1-3 mol%. This contribution could become an important starting point for further investigations opening a new line of research overlooked so far in the literature.
Keywords. thiourea, gold, asymmetric, organocatalysis, synergy
Section Board for ‘Organic Synthesis’
Dr. Raquel P. Herrera
Laboratorio de Organocatálisis Asimétrica, Instituto de Síntesis Química y Catálisis Homogénea (CSIC-UZ), Departamento de Química Orgánica, Facultad de Ciencias Plz. de San Francisco s/n, Universidad de Zaragoza, E-50009 Zaragoza, Spain
Website | E-Mail
Interests: thiourea; indole; organocatalysts; hydrogen bond; Michael addition
Special Issues and Collections in MDPI journals:
Topical Collection: Recent Advances in Organocatalysis
Last Sunday, Raquel won the Gold medal in the category of walkers in the solidary race 7K AL RESCATE DEL CEREBRO. AIDA ICTUS Y ALZHEIMER ARAGON
Congratulations!
Raquel, after winning the race.
Juanvi is now one year wiser 😉
Congratulations!
Blowing a “candle”
Nice Spanish omelette!
HOCA group wishes you all the best, now and ever!
This is the first article of a synergistic collaboration between Southampton and Zaragoza, as well as the catalysis involved on it. The work has been developed in Dr. Ramon Rios’s lab at the University of Southampton, in collaboration with Prof. M. Concepción Gimeno and Dr. Raquel P. Herrera. This article is part of a Special issue dedicated to Prof. Dieter Enders. Congratulations!
Synergistic Catalysis: Asymmetric Synthesis of Cyclopentanes Bearing Four Stereogenic Centers. Zhang, K.; Meazza, M.; Izaga, A.; Contamine, C.; Gimeno, M. C.; Herrera, R. P.; Rios, R. Synthesis, 2017, 49, 167–174.
Abstract. We present a formal [3+2] cycloaddition based on synergistic catalysis. Vinylcyclopropanes derived from cyanoesters react with enals by dual activation using palladium(0) and secondary amines to form the corresponding cyclopentanes in good yields and stereoselectivities.
Key words. synergistic catalysis – organocatalysis – cyclopentanes – asymmetric synthesis – cycloaddition.
Herrera-OrganoCatalisis Asimétrica Group 