Gold Catalyzed Multicomponent Reactions beyond A³Coupling

Renso Visbal, Sara Graus, Raquel P. Herrera, M. Concepción Gimeno

Molecules 2018, 23(9), 2255. https://doi.org/10.3390/molecules23092255

Abstract: The preparation of complex architectures has inspired the search for new methods and new processes in organic synthesis. Multicomponent reactions have become an interesting approach to achieve such molecular diversity and complexity. This review intends to illustrate important gold-catalyzed examples for the past ten years leading to interesting skeletons involved in biologically active compounds.

Keywords: β-alkoxyketones; butenolides; catalysis; ethers; gold; 3,4-dihydropyrimidin-2(1H)-ones; 1,4-dihydropyridines; multicomponent reactions; oxazoles; pyridines; spirocycles; thiazolo-quinolines