Asymmetric Organocatalysis in Total Synthesis – A Trial by Fire. Marqués-López, E.; Herrera, R. P.; Christmann, M. Nat. Prod. Rep. 2010, 27, 1138-1167.
From September / October 2017, this much-cited article received enough cites to be included in the 1% of the best articles of the Academic area of Pharmacology & Toxicology based on a threshold of articles very cited for the area and the year of publication. (Data of Essential Science Indicators).
Last December, 15th Juanvi defended his PhD thesis with great honors.
We are really proud of you.
Good luck and enjoy life!
All the best for you, my little angel.
I love you.
HOCA PhD students joined last week, the XIV Simposio de Investigadores Jóvenes de la RSEQ, celebrated in Badajoz (Spain).
Juanvi gave a talk about “PUSH-PULL” π+/π- (PPππ) SYSTEMS: A NEW TYPE OF INTERACTION SYSTEM IN CATALYSIS.
Fernando and Isaac presented their posters about ORGANOCATALYTIC SYNTHESIS OF 4H-PYRAN DERIVATIVES and SYNTHESIS OF ENANTIOMERICALLY ENRICHED β-NITROHYDRAZIDAS, respectively.
Hunting a Pokemon while setting up reactions…
Juanvi has been in Arantzazu (Gipuzkoa), from October 16th to 19th working with other PhD students in the “Doctoriales transfronterizos UPPA-UPV/EHU” (UPPA-UPV / EHU Transboundary Doctorials), organized by the Master’s and Doctorate School of the UPV / EHU (MDe), in collaboration with the University of Pau et des Pays de l’Adour (UPPA).
He met a lot of new people, and learnt a lot in these intensive days.
Juanvi has worked hard in this project and now the first results have just come out. The central idea is to generate in situ, the carbonyl compound, via oxidation of an alcohol, which is involved in a subsequent asymmetric organocatalytic reacion (Henry and aldol reactions). This makes in general, the reactions more efficient.
Congratullations!
Organocatalyzed enantioselective aldol and Henry reactions
starting from benzylic alcohols, Alegre Requena J. V.; Marqués-López, E.; Herrera, R. Adv. Synth. Catal. 2017, DOI: 10.1002/adsc.201701351.
Abstract. Pioneering aldol and Henry reactions starting from alcohols are described. The aldol reaction has been successfully performed following a one-pot strategy starting from alcohols, while the Henry reaction has been carried out following a sequential protocol for the first time. In both processes, enantiomerically enriched products were obtained with good yields and high enantioselectivities. We have also demonstrated that in reactions sensitive to small amounts of acid the use of alcohols instead of aldehydes could be a good solution for improving the results of these reactions.
Keywords. alcohol; aldehyde; aldol; Henry; MnO2; organocatalysis; one-pot; oxidation.
Raquel, along with colleagues and friends, ran once again for a solidary reason the “Carrera de la MUJER” in Zaragoza.
Greetings to all women!
We want to give our warmest welcome to Sofía to our group. She will work on her Master thesis dealing with the synthesis of metal-squaramide complexes and the study of their properties. Good luck!
Last 28th September, Javi presented his Bachelor thesis (TFG) and he got a good mark. Congratulations!
He is now studying a Master in Madrid. We wish him all the best!
Come to visit us with peaches soon! 😉
Little present from your Alma mater University…
Herrera-OrganoCatalisis Asimétrica Group 