Last summer Sandra spent 3 months at Universität Münster, working in García Mancheño Group. She enjoyed a lot and also ensured nice fruits. Thank you, Olga, for being open for collaboration and hosting our girl!

Congratulations for this first article!

Hydrogen-Bonding Organocatalysis Enabled Photocatalytic Intramolecular [2+2]-Cycloaddition Reaction, Stefania Perulli, Om Desai, Sandra Ardevines, Mustafa Uygur, Samuel Delgado-Hernández, Olga García Mancheño Adv. Synth. Catal. 2024, 366, 751-756 (https://doi.org/10.1002/adsc.202301217)

Abstract. The combination of organocatalytic activation and photocatalysis for enabling the intramolecular [2+2]-cycloaddition of enone-ene substrates bearing one Lewis base binding site is reported. While in a variety of solvents a poor conversion or no reaction takes place in the absence of a hydrogen bonding catalyst, the corresponding ring-fused cyclobutane products could be built in moderate to good yields using a synergistic dual iridium-urea co-catalytic system. Control and mechanistic studies supported the postulated interaction between the organocatalyst and the substrate, which proved essential for an efficient energy transfer from the photosensitizer.